Program

Preliminary program
Program might be subject to changes

Session topics

Metabolism = Phospholipids, sterols & metabolism
Contact = Protein-membrane interactions & inter-organelle membrane contact sites
Cell factory = Yeast as a platform for lipid production

Wednesday 1 June 2022

Session 1 - Metabolism

Session chair: Toon de Kroon

StartEndActivitySpeakerTitle / description
10:0010:45RegistrationWelcome coffee available. Please hang up your posters
10:4511:00WelcomeYLC2022 organizers
11:0011:30InvitedUroš Petrovič
Jožef Stefan Institute, Slovenia
Regulation of neutral lipid storage in S. cerevisiae
11:3011:45SelectedCarolin Körner
University of Osnabrück, Germany
In vitro characterization of serine palmitoyltransferase in S. cerevisiae
11:4512:00SelectedJohn Reinhard
Saarland University, Germany
Liquid-liquid phase separation in live yeast vacuole membranes correlates with a shift of phosphatidylcholines towards higher melting temperatures
12:0012:30InvitedAlwin Köhler
Max Perutz Labs Vienna, Austria
Lipid metabolism of the nuclear envelope
12:3013:30Lunch break

Session 2 - Metabolism

Session chair: Symeon Siniossoglou

StartEndActivitySpeakerTitle / description
13:3014:00InvitedRoger Schneiter
University of Fribourg, Switzerland
Perilipin 3 binds diacylglycerol and induces the formation of membrane domains enriched in lipid droplet biogenesis proteins
14:0014:15SelectedBrianna Greenwood
University of Alberta, Canada
The desaturasome: a multi-protein complex that controls lipid biosynthesis in S. cerevisiae
14:1514:30SelectedGeorge Carman
Rutgers University, USA
Phosphatidic acid mediates the Nem1-Spo7/Pah1 phosphatase cascade in S. cerevisiae
14:3014:45SelectedMohammad Tanvir Rahman
University of Oulu, Finland
An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration
14:4515:00SelectedRodrigo de Almeida
Universidade de Lisboa, Portugal
Targeting yeast sphingolipids by the antifungal polyene Nystatin
15:0015:45Coffee break

Session 3 - Metabolism

Session chair: George Carman

StartEndActivitySpeakerTitle / description
15:4516:15InvitedMartin Graef
Cornell University, USA
Defective lipid buffering impairs autophagosome biogenesis
16:1517:15KeynoteMiriam Greenberg
Wayne State University, USA
Using the yeast model to explore the role of perturbation of cardiolipin metabolism in Barth syndrome
17:1517:30Biobreak

Session 4 - Poster flash

StartEndActivitySpeakerTitle / description
17:3018:30Poster flashPoster presentersOdd numbered abstracts
18:3020:00Welcome reception and mingle foodPoster session for odd numbered abstracts

Thursday 2 June 2022

Session 5 - Contact

Session chair: Doron Rapoport

StartEndActivitySpeakerTitle / description
08:3009:00InvitedYasushi Tamura
Yamagata University, Japan
Regulation of phospholipid transport between the ER and mitochondria
09:0009:15SelectedAndreia Bento-Oliveira
Universidade de Lisboa, Portugal
Impact of sphingolipid hydroxylation and polar headgroup on yeast lipid domains and membrane protein compartments
09:1509:45InvitedJieqiong Gao
University of Osnabrück, Germany
Insights into the biogenesis of signaling endosomes in yeast
09:4510:15Coffee break

Session 6 - Contact

Session chair: Snezhana Oliferenko

StartEndActivitySpeakerTitle / description
10:1510:45InvitedOfir Klein
Weizmann Institute of Science, Israel
Mapping contact site proteomes by high content screening uncovers new players in mitochondrial homeostasis
10:4511:00SelectedCynthia Alsayyah
Saarland University, Germany
Mitofusin-mediated contacts between mitochondria and peroxisomes indirectly regulate mitochondrial fusion
11:0011:15SelectedTim Levine
University College London, UK
Systematic analysis of membrane contact sites in S. cerevisiae uncovers YPR097w/Lec1 as a novel type of “large” lipid transfer protein that modulates ergosterol distribution
11:1511:30Biobreak

Session 7 - Poster flash

StartEndActivitySpeakerTitle / description
11:3012:30Poster flashPoster presentersEven numbered abstracts
12:3014:00Lunch breakPoster session for even numbered abstracts

Session 8 - Contact

Session chair: Tim Levine

StartEndActivitySpeakerTitle / description
14:0014:30InvitedSnezhana Oliferenko
Francis Crick Institute, UK
Exploiting divergent biology of two fission yeasts to understand membrane function
14:3014:45SelectedMaria Isabel Geli
Institute for Molecular Biology of Barcelona, Spain
Role of sterols and ceramides at ER-endocytic contact sites
14:4515:00SelectedPatrick Rockenfeller
University of Witten/Herdecke, Germany
Lipids in Yeast Autophagy – a special focus on phosphatidylethanolamine, Porin 1 and phosphatidylserine decarboxylase 1
15:0015:30Coffee break

Session 9 - Cell factory

Session chair: Inge van Bogaert

StartEndActivitySpeakerTitle / description
15:3016:00InvitedZbigniew Lazar
University of Wrocław, Poland
Regulation of sugar metabolism and its influence on lipid biosynthesis in the yeast Yarrowia lipolytica
16:0016:15SelectedAlexandra Daskalaki
University of Patras, Greece
Enhancement of lipogenesis in Yarrowia lipolytica through adaptive laboratory evolution
16:1516:30SelectedAlina Rekena
Tallinn University of Technology, Estonia
Metabolic flux and proteome analysis of lipid production in Rhodotorula toruloides
16:4517:30Walk to cruise
18:0021:00Dinner

Friday 3 June 2022

Session 10 - Cell factory

Session chair: Rodrigo Ledesma Amaro

StartEndActivitySpeakerTitle / description
08:3009:00InvitedMartin Grininger
Goethe University Frankfurt, Germany
Engineering fatty acid synthases (FASs) for custom compound synthesis
09:0009:15SelectedJose Manuel Salvador Lopez
Ghent University, Belgium
Oleaginous yeasts: Time to rethink the definition?
09:1510:00InvitedHuimin Zhao
University of Illinois at Urbana-Champaign, USA
Modeling and engineering of yeast lipid metabolism
10:0010:30Coffee break

Session 11 - Cell factory

Session chair: Petri-Jaan Lahtvee

StartEndActivitySpeakerTitle / description
10:3010:45SelectedFlorence Bordes
Toulouse Biotechnology Institute, France
A panel of genetic tools to easily engineer the yeast Yarrowia lipolytica
10:4511:00SelectedHarald Pichler
Graz University of Technology, Austria
Evolving sterol acyltransferase Are2p in S. cerevisiae for vitamin D3 production
11:0011:15SelectedJean-Marc Nicaud
INRAE, France
Lipid readjustment in Yarrowia lipolytica odd-chain fatty acids producing strains
11:1511:45InvitedInge van Bogaert
Ghent University, Belgium
The role of transport proteins in lipid production by Starmerella bombicola
11:4512:00ClosingAwards, closing, YLC2024
12:00Take-away lunch